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Using two separate drugs to lose weight naturally can be very effective you will find combinations in front of the FDA now awaiting approval. When dealing with fat loss and the people that go through it you ought to err to the side of caution and allow the FDA do its job and demand some research be done so that the public is aware of the side effects and risks of the medications before we bring them. Keep in mind that drug companies have been in business to generate income and that they would say almost anything to keep people on his or her medications. Researchers discovered that participants investing in this drug to get a year, dropped a few pounds within four weeks and have kept the body weight off through the 56 weeks in the study. Contrave is really a combination with the drugs naltrexone and bupropion, which generally seems to reflect a new trend of weight-loss drugs that are made up of multiple active ingredient, which can make them more effective and safer. Combo-pilling is the newest fad or better yet the newest into the future under scrutiny and so it is just more publicly known recently, comb-pilling to lose weight has been around since the eighties. The biggest reason that employing a combination of pills is now popular is the fact that since right now there are no long term prescription slimming capsules that have been authorized by the FDA apart from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications however some of the combinations have been rejected or have yet to be approved by the FDA. Seizures are a side effect with Contrave and must not be taken in those with seizure disorders. The drug also can raise blood pressure level and heartrate, and mustn't be used in people with a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with the drug. The FDA also warned that Contrave can raise blood pressure and heartrate and must 't be used in patients with uncontrolled high blood pressure level, and also by anyone with heart-related and cerebrovascular (circulation dysfunction impacting your brain) disease. Patients using a history of heart attack or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes using a boxed warning to alert medical professionals and patients towards the increased probability of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stopping smoking. From a psychiatric point of view, evidence points too the ordinary neural mechanism for goal-directed behavior has been hijacked from the addiction, and malfunctions such that its ordinary functions are exaggerated and fixated on its object. An object produces a stimulus and also the person engages in a "goal-directed behavioral response" that generates a "natural high"(Bostwick & Bucci, 2008).