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Contrave is really a combination from the drugs naltrexone and bupropion, which usually reflect a brand new trend of weight-loss drugs which are made up of several active ingredient, which might make them more effective and safer. Combo-pilling may be the newest fad or better yet the newest to come under scrutiny and so it is just more publicly known although in the past, comb-pilling for losing weight has been around since the eighties. The biggest reason that employing a combination of pills is becoming popular could be the fact that at the time of right now there aren't any long term prescription weight loss supplements that have been authorized by the FDA besides orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications even though some of the combinations are actually rejected or have yet to be authorized by the FDA. Seizures certainly are a side effect with Contrave and shouldn't be taken in people who have seizure disorders. 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